. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. CALMODULIN AND SPISULA OOCYTES 45 RESULTS Calmodulin antagonists can block GVBD Since KC1 induces GVBD rapidly and synchronously in oocytes in this species, and KCl-induced GVBD would be independent of possible indirect inhibition through inhibition of fertilization, we initially tested the ability of calmodulin antagonists to prevent GVBD on KCl-activated oocytes. Figure 1 shows that all calmodulin antag- onists tested blocked GVBD in Spisula oocytes when induced by KC1. The results also show that calmidazolium is maximally

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. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. CALMODULIN AND SPISULA OOCYTES 45 RESULTS Calmodulin antagonists can block GVBD Since KC1 induces GVBD rapidly and synchronously in oocytes in this species, and KCl-induced GVBD would be independent of possible indirect inhibition through inhibition of fertilization, we initially tested the ability of calmodulin antagonists to prevent GVBD on KCl-activated oocytes. Figure 1 shows that all calmodulin antag- onists tested blocked GVBD in Spisula oocytes when induced by KC1. The results also show that calmidazolium is maximally
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. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. CALMODULIN AND SPISULA OOCYTES 45 RESULTS Calmodulin antagonists can block GVBD Since KC1 induces GVBD rapidly and synchronously in oocytes in this species, and KCl-induced GVBD would be independent of possible indirect inhibition through inhibition of fertilization, we initially tested the ability of calmodulin antagonists to prevent GVBD on KCl-activated oocytes. Figure 1 shows that all calmodulin antag- onists tested blocked GVBD in Spisula oocytes when induced by KC1. The results also show that calmidazolium is maximally

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