Stock fotóügynökség Magyarország | Egyedi Stock fotó

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This photo uses confocal microscopy and merges 350 individual images to reveal a top view of a zebrafish with a fluorescent and quottagged and quot skeleton, scales and lymphatic system. The image was awarded by NIH researcher Daniel Castranova and won 1st place in Nikon's 2020 photomicrography competition.-stock-foto

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This image shows collagen, a fibrous protein that is the main component of the extracellular matrix (ECM). Collagen is a strong, rope-like molecule that forms stretch-resistant fibers. The most abundant protein in our body, collagen makes up about a quarter of our total protein mass. Among its many functions, it gives strength to our tendons, ligaments and bones and provides a scaffold for the healing of skin wounds. There are approximately 20 different types of collagen in our body, each tailored to the needs of specific tissues-stock-foto

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These skin cancer cells show from a mouse, an animal commonly used to study human diseases (including many types of cancer) and to test the effectiveness of drugs. The two cells contained here are linked by actin (green), a cell skeleton protein. Although actin is required by many cells for normal movement, it also allows cancer cells to spread to other parts of the body.-stock-foto

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This image shows mouse muscle cells seen under a microscope. The cells have fused to form myotubes which have many nuclei (stained blue). The cells produced from mouse skeletal muscle stem cells with a harmless virus that made them glow green. The green color remained when the stem cells fused into myotubes. Some myotubes are stained red for a protein involved in muscle contraction (myosin heavy chain), a characteristic of mature muscle fibers. Researchers should use the same viral delivery system to genetically modify cells and assess how altering cell fusion impairs myotube growth.-stock-foto

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This cross section of regenerated muscle shows muscle stem cells (red) in their niche along muscle fibers (green). The blue dots are the DNA in the fiber nuclei. Researchers have found that injecting the molecule prostaglandin E2 into muscles after injury induces the division of muscle stem cells and accelerates regeneration. Prostaglandin E2 is an inflammatory molecule released in response to muscle injury or rigorous exercise.-stock-foto

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This is a scanning electron microscope image of traumatized muscle tissue taken from a wounded soldier. It shows a red blood cell (false color) entangled in a nanofibrous extracellular matrix. Highly fibrotic regions such as these are thought to precede bone formation during abnormal wound healing, leading to heterotopic ossification, the formation of bone in places outside the skeleton, such as soft tissues.-stock-foto

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Myelinated axons in a rat vertebral root. Myelin is a type of fat that forms a sheath around and thus insulates the axon to protect it from the loss of the electrical current needed to transmit signals along the axon. The axoplasm inside the axon is shown in pink.-stock-foto

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Of the three muscle fibers shown here, the one on the right and the one on the left are normal. The middle fiber is deficient a large protein called nebulin (blue). Nebulin plays a number of roles in the structure and function of muscles, and its absence is associated with certain neuromuscular disorders.-stock-foto

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$Osteochondrotricular stem cells (red) are a newly identified type of bone stem cell that appears to be vital for skeletal development. Research on these stem cells could lead to treatments for osteoarthritis, osteoporosis and fractures.-stock-foto$

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The cerebellum of a mouse is shown here in cross section. The cerebellum is the locomotion control center of the brain. Every time you shoot a basketball, tie your shoe, or chop an onion, your cerebellum springs into action. Located at the base of your brain, the cerebellum is a single layer of tissue with deep folds like an accordion. People with damage to this area of the brain often have difficulty with balance, coordination, and fine motor skills.-stock-foto

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Adult-like heart tissue engineered from human pluripotent stem cells contains transverse tubules, the mark of maturity, visible on immunofluorescent images. Researchers can now use induced pluripotent stem cells (iPSCs) to train an adult-like model of human heart muscle by introducing electrical and mechanical stimulation at an early stage. Since this muscle is similar to the adult heart, it could serve as a better model for testing the effects of drugs and toxic substances than current tissue-engineered heart models.-stock-foto

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Immature muscle cells fuse during development to form long muscle fibers with many nuclei. To identify the factors involved in the fusion process, the scientists studied fibroblast cells that do not fuse normally. As shown in the microscopic image, adding a gene that makes a protein called myomerger to fibroblasts causes them to fuse into clusters of fluorescently stained cell nuclei. The protein works in tandem with another protein, called myomaker, to cause fusion.-stock-foto

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Jellyfish are particularly good models for studying the evolution of embryonic tissue layers. Although they are primitive, jellyfish have a nervous system (colored in green here) and a musculature (red). Cell nuclei are stained blue. By studying the distribution of tissues in this simple organism, scientists can learn about the evolution of shapes and characteristics of various animals.-stock-foto

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Strands of tubulin, a cell skeletal protein, photographed using a high-resolution microscopy technique that won the 2014 Nobel Prize in Chemistry.-stock-foto

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This photograph depicts Drosophila melanogaster, better known as the fruit fly, in flight while tied with tungsten wires. Capable of flapping its wings 200 times per second, the fruit fly is a wonderful creature. By taking still photographs with exposure times on the order of a hundredth of a second, the mechanics of the wing flapping can be revealed. This image is part of a student project investigating mutations in myosin, a muscle protein that causes familial hypertrophic cardiomyopathy (a disease of the heart muscle).-stock-foto

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The cerebellum is the locomotion control center of the brain. Located at the base of your brain, the cerebellum is a single layer of tissue with deep folds like an accordion. People with damage to this area of the brain often have difficulty with balance, coordination, and fine motor skills.-stock-foto

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This is a microscopic view of lab-grown human muscle bundles, colored to show the patterns created by the basic muscle units and their associated proteins (red), which are a hallmark of human muscle. These lab-grown human muscle tissues allow researchers to test new drugs and study diseases in muscle tissue outside the human body.-stock-foto

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Daniel Marks and his colleague Kevin Grove of Oregon Health and Science University studied the effects of a high-fat diet on developing organs using a non-human primate animal model. These photographs show the livers of fetuses from monkeys whose mothers had been fed either a regular low-fat diet (control) or a high-fat, high-calorie diet. The livers were treated with a compound (oil-red O) which stains fat deposits red.-stock-foto

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Diaphragmatic muscle from a dystrophin-deficient mouse treated with SU9516 showing nuclei (blue), myofibers (boxed in red) and regenerating muscle fibers (green).-stock-foto

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Intertwined muscle fibers of a rat's tongue. This complex muscular anatomy allows for the complex movements of the tongue necessary for vocalizations and swallowing.-stock-foto

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Pompe disease is a rare hereditary disease characterized by the deficiency of an enzyme called acid alpha-glucosidase (GAA). One of the main features of Pompe disease is the progressive breakdown of communications between nerve and muscle cells. This image is of a leg muscle (tibialis anterior) from an adult mouse model of Pompe disease. Nerve cells (green) and cellular nerve-muscle communication sites, called neuromuscular junctions, (red) are fluorescently labeled to observe the continued deterioration of neuromuscular junctions.-stock-foto

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Researchers have determined that the TFIID protein complex controls the stem cell genes that repair skeletal muscle. This image shows differentiated human skeletal muscle fibers (myotubes, in green) protecting the MyoD protein (colored in red), which cooperates with TFIID to transform muscle stem cells into muscle tissue. Cell nuclei are stained blue. This discovery could help develop strategies that activate stem cells to repair muscles degenerated by aging or diseases like muscular dystrophy and cancer.-stock-foto

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A microscopic image of liver tissue affected by non-alcoholic fatty liver disease (NAFLD). The large and small white spots are excess fat droplets that develop liver cells (hepatocytes).-stock-foto

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Immunofluorescence image of actin bundles in muscle precursor cells called myoblasts. Actin is labeled with fluorescently labeled phalloidin, which is a toxin from the fungus Amanita phalloides. Nuclei are shown in blue.-stock-foto

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This image shows the crimp (ripple) pattern of collagen fibers in a medial collateral ligament, which is the ligament on the inside of the knee. The ligament section was magnified to 200X using polarized light microscopy.-stock-foto

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This pig cell is dividing. The chromosomes (purple) have already replicated and the duplicates are separated by fibers in the cell skeleton called microtubules (green). Cell division studies provide essential knowledge to advance the understanding of many human diseases, including cancer and birth defects.-stock-foto

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Embryonic smooth muscle cell. Immunofluorescence-labeled actin cytoskeleton (green) and vinculin in cell adhesions (blue). Confocal laser scanning microscopy.-stock-foto

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This image shows a normal fibroblast, a cell type common in connective tissue and frequently examined in research laboratories. Unlike the spiky version, this cell has a healthy skeleton composed of actin (red) and microtubules (green). Actin fibers contain like muscles to create tension and microtubules contain like bones to resist compression.-stock-foto

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It is a fibroblast, a connective tissue cell that plays an important role in wound healing. Normal fibroblasts have smooth edges. On the other hand, this bristly cell lacks a protein necessary for the proper construction of the cell and the skeleton.-stock-foto

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In these images from Gabrielle Kardon's NIH-supported lab at the University of Utah, Salt Lake City, you see the developing forelimb of a healthy mouse strain (top) compared to that of a mutant mouse strain with a stiff, abnormal gait (bottom).-stock-foto

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This image shows an osteosarcoma cell with DNA in blue, energy factories (mitochondria) in yellow, and actin filaments, part of the cell skeleton, in purple. Osteosarcoma, one of the rare cancers that originate in the bones, is extremely rare, with less than a thousand new cases triggered each year in the United States.-stock-foto

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NIAMS scientists found evidence that high numbers of osteoclasts, a type of cell that breaks down bone, may contribute to bone loss in people with spondyloarthritis. Osteoclasts, like the one shown here in the center, contain multiple nuclei (light circles) because they are formed by fusion of precursor cells.-stock-foto

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More than just a rigid organ, bone is porous and has living cells. Knowing the structure of bone is key to understanding how nutrients are delivered and the signals transmitted between bone cells. Using fluorescence, the network of bone cells is imaged under a microscope. The vast branch-like structures (upper left) are dependent highways of isolated bone cells. And bone cells form a solar system-like structure, following pink traces of collagen in cross sections (bottom left).-stock-foto

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$During normal bone development and fracture healing, cartilage turns into bone. Osteoclasts, a type of specialized cell, eat cartilage, provide passage for blood vessels, marrow and other bone cells. In this image of cartilage (purple and white) from a young mouse femur, osteoclasts (red) surround a blood vessel filled with red blood cells (yellow). Unlike normal osteoclasts, the cells present here have only one nucleus due to the absence of a gene involved in osteoclast development.-stock-foto$

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Joint tissues from patients with rheumatoid arthritis (RA) contain high numbers-stock-foto

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Colorized scanning electron micrograph of a cell infected with a variant strain of SARS-CoV-2 virus particles, isolated from a patient sample. Image requested from the NIAID Integrated Research Facility (IRF) in Fort Detrick, Maryland. Credit: NIAID-stock-foto

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Actin is an essential protein in the skeleton of a cell (cytoskeleton). It forms a dense network of fine filaments in the cell. Here, the researchers used a technique called stochastic optical reconstruction microscopy (STORM) to visualize the actin network in a cell in three dimensions. Actin strands were labeled with a dye called Alexa Fluor 647-phalloidin. This image appears in a study published by Nature Methods, which reports how researchers use STORM to visualize the cytoskeleton.-stock-foto

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Contraction of microtubules. Top, microtubules (blue) in a resting cardiac muscle cell. Bottom, contracted microtubules (blue) in a moving cardiac muscle cell.-stock-foto

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